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Clinical enthusiasm should remain tempered until larger, independently conducted trials establish both safety and efficacy

[DOI] [PubMed] [Google Scholar] 17.Extended duration infusion of high-dose hydroxocobalamin for vasoplegic syndrome following cardiac surgery

This can change based on how well the patient responds

It occupies a different mechanistic category from cognitive peptides like Semax or energy peptides like NAD+, which means there is no redundancy in combining them