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Description

Neuropathology of amyotrophic lateral sclerosis and its variants

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The resulting -hydroxy-1, N 2 -propanoguanine-modified oligodeoxynucleotide was mixed at a 1:1 molar ratio with the complementary oligo: 5-[phos]-CCC TCT TCC GCT CTT CTT TC-3 in PBS and annealed at 85 C for 5 min, ramped to 25 C at 0.1 C s-1 and flash frozen immediately to prevent crosslink formation

References Dolma S, Lessnick SL, Hahn WC, Stockwell BR

There were many differences between the treatments used by the good responders and mild responders so there is a lot of possible "confounding factors"