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Tissue ferritin is released by iron-damaged hepatocytes and Kupffer cells in iron overload conditions and has been shown to act as an iron-independent proinflammatory mediator of hepatic stellate activation as a portent to fibrogenesis [84], acting via a high affinity binding protein for H-subunit ferritin (FTH) [93]

[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Lucock M

This highlights a potential connection between systemic eryptosis and local peritoneal inflammation, while confirming that eryptosis is primarily influenced by blood compositionespecially in inflammatory states