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B12 plays an important role in neurotransmitter production, which influences mood regulation and stress resilience

Although the use of fibroblasts allowed to understand the general metabolic alterations occurring in the TDP-43 G376D carrying cells, and particularly the role of oxidative stress, further studies on more complex cell models of ALS should be performed, including metabolomic analysis that will complement Seahorse data

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In the context of PD, a variety of compounds from each class have shown beneficial effects (13)