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Introduction and Conceptual Framework Asthma is a complicated disorder characterized by variable and recurrent episodes of airway inflammation and airflow limitation in response to specific triggers

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Briefly, cells were maintained in growth medium (High-glucose Dulbeccos modified Eagles medium (DMEM) supplemented with 10% FBS, 2 mM L-glutamine, 100 U/ml penicillin, 100 mg/ml streptomycin (all from Thermo Fisher Scientific Waltham, MA, United States))

In this review we focus on the interaction between tNs and endogenous glia, with particular attention to the oligodendrocyte lineage cells (OLs)