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Kuka J, Videja M, Makrecka-Kuka M, et al

Experimental aspect of BPC-157 action on the nervous system Study 1 Material The study was conducted on rats using the cuprizone toxin, which allows the achievement of disease symptoms similar to those occurring in multiple sclerosis or schizophrenia

4.3 Mitochondrial redox signaling as a bidirectional regulator of sleep and cellular homeostasis Mitochondria are the primary source of intracellular ROS, generating approximately 90% of cellular ROS as byproducts of oxidative phosphorylation (Balaban et al., 2005)

Pre-clinical studies indicate that this suppression may exacerbate liver damage