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Supplementation may slow the progressive deterioration of function in Parkinson's disease (Shults 2002) and have a neuroprotective effect

CYP 450 Families and subfamilies Foye's principles of medicinal chemistry CYP Biotransformations Chemically diverse small molecules are converted, generally to more polar compounds Reactions include: Aliphatic hydroxylation, aromatic hydroxylation Dealkylation (N-,O-, S-) N-oxidation, S-oxidation Deamination Dehalogenation Oxidative Phase-I involving cytochrome P-450 enzymes: Aliphatic hydroxylation: Mainly occur on the ultimate () or penultimate (-1) carbon atom in the structure

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