chac1 er stress glutathione degradation TRIB3 increases cell resistance to arsenite toxicity by limiting the expression of the glutathione-degrading enzyme Long noncoding RNA GDIL acts

Long noncoding RNA GDIL acts as a scaffold for CHAC1 and XRN2 to promote platinum resistance of colorectal cancer through inhibition of glutathione degradation Cell Death & Disease CHAC1 degradation of glutathione enhances cystine starvation induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2 eIF2 ATF4 pathway Oncotarget A scheme of the mechanism of CHAC1 degradation of glutathione enhancing Download Scientific Diagram This figure illustrates the interactions and regulatory mechanisms Download Scientific Diagram

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