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In preclinical adipocyte models, studies suggest this shift in metabolic flux is associated with changes in lipogenic gene expression, including reduced expression of key adipogenic transcription factors

Interestingly, although the referent group showed a slight increase in systolic blood pressure (+0.5-3.2 mmHg) at twenty-four months, all groups had slightly lower systolic blood pressure than the referent group at twelve- and twenty-four-months follow-up period