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Antiviral Res

Based on previous experiences with SARS and MERS, Yang and his team developed a blood (serum/plasma) purification protocol for patients with COVID-19 sufferers that included four main steps: 1) deciding whether chronic COVID-19 patients need blood purification

Treatment of NPC1-null cells with the mTOR inhibitor Torin1 or downregulation of mTORC1 activity via knockdown of LAMTOR5 restores impaired lysosomal and mitochondrial functions in these cells

DLin-MC3-DMA was integral to the development of the first FDA-approved siRNA drug, Onpattro, and has been proven effective for mRNA delivery in vivo