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Teplensky et al

Human and animal work show that elevations in cytokines, when triggered by infection, exogenous immune stimulation, or sleep deprivation, generally promote increases in total sleep duration, longer non-rapid eye movement (non-REM) sleep duration and increased slow-wave activity, often with concurrent reductions in REM sleep and reduced sleep continuity [1, 4,5,6,7,8]

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This is in contrast to animals treated intraperitoneally or intrathecally with IgG-anti-amphiphysin Abs who have exhibited a clear stiffness-like behavior [61, 62]