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An analysis based on elevated total cysteine (above the median) and low GSH-T (below the median) showed a similar result on GlyNAC efficacy in this subpopulation (medians, V2 = 817.7, V4 = 859.3 mg/L per %Ht, p -value = 0.015) (Supplementary Figure S3)

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Fibroblast activation protein: a serine protease expressed at the remodeling interface in idiopathic pulmonary fibrosis

Dashed arrows represent reported side-reactivities of LDOX observed in vitro