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These results suggest that Hcy-induced hypomethylation of DNA, RNA, protein in ECs leads to endothelial injury by impairing water permeability, inducing inflammation, and inhibiting proliferation

However, studies on their combined use are still limited, and it is not yet clear whether using them together provides better results than using either peptide alone

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Methods Patients Of the 53 patients with FCMD who had attended Tokyo Womens Medical University and agreed to participate in the study, 9 patients were excluded as they were unable to visit the hospital for evaluation, 1 had unclear genetic testing, and 1 was an infant with an unclear clinical form (Fig