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(2016) found that withaferin A is a strong inducer of Nrf2, a transcription factor that controls the production of antioxidant enzymes in response to oxidative stress through activation of the PTEN/PI3K/Akt pathway [146]

Figure 1 Nevertheless, the current data remains fragmented by considerable methodological heterogeneity

LW: Writing review & editing, Writing original draft, Supervision, Project administration, Methodology

In competitive interaction assays, 34 nM Cy5-labeled-PDS5B and gradient-diluted concentrations of Wapl were combined to enable interaction at RT for 10 min, Sororin and RSMC were then added to the mixture before the measurements