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Circular RNAs (circRNAs) are a class of single-stranded non-coding RNAs that form circular conformations through non-canonical splicing or back-splicing events, and play a key role in the occurrence and development of a variety of tumors [155, 156]

However, during 20182019, it prevented around 4.4 million influenza illnesses, 2.3 million influenza-associated medical visits, 58,000 influenza- associated hospitalisations and 3,500 influenza-associated deaths in the US. 1,2 Each of the COVID-19 vaccines was tested in thousands of patients of varying ethnicities and some with medical conditions, for example, lung and heart disease, but were otherwise initially mostly tested in individuals without cancer