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A., Labuda, T., Karin, M

HOCl is a strong oxidant (E 0 [HOCl/Cl ] = + 1.28 V) and also the active ingredient of household bleach [217]

We assessed the stability of the 3Br-5MPs by incubating 3a under various conditions and found that it, similar to the 5MP counterpart 5 (Fig

the net result is compromised NO physiologic effects by this simultaneous, dual action of: (i) removing NO by the formation of peroxynitrite, and (ii) the consumption of NO by myeloperoxidase activity