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Age and Sex of Subjects: These are often overlooked but incredibly important

Although the precise etiology of PD remains unclear, factors such as oxidative stress, lipid metabolism dysregulation, metal ion metabolic disorders, mitochondrial dysfunction, and glial cell activation are known to contribute to the progression of PD, suggesting that ferroptosis plays a significant role in its pathogenesis (Wang ZL

The highest IGF-1 expression occurs in the subendocardial layer, where the wall stress is more pronounced,117 suggesting a possible role as a mediator of left ventricular hypertrophy

Normal urine pH typically ranges from 4.5 to 8