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This effect may be due to spike protein inducing negative mitochondrial membrane potential, increasing intracellular calcium, and increasing levels of reactive oxygen species (ROS)

There are no known enzyme(s) that specifically neutralize hydroxyl radical (OH ) since this ROS nonselectively reacts with the nearest nucleophilic molecule that it encounters [3, 4]

The results of metabolomics and lipidomics analysis revealed that numerous lipid species in human plasma, including fatty acids, triacylglycerols, glycerophospholipids, sterol lipids, and sphingolipids, are regulated by circadian rhythms [49]

This observation is in agreement with Enechi and Ozogwu, [47] and suggests the potential of M