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Physical Activity & Sweat Based Elimination Cardiovascular training Strength training Heat exposure - sauna *Sweat is not a major detox route compared to liver/kidneys, but it does excrete meaningful amounts of certain compounds* Can be : some heavy metals, BPA, Phthalates, some flame retardants (PBDEs), some pesticides, VOC metabolites, small organic pollutants (PAH) Cannot be : PFAS, Dioxins & Furans, PCBs, some flame retardants (OPFRs), micro & nanoplastics, formaldehyde, carbon monoxide, hydrogen cyanide 5

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We found elevated AA significantly correlated with decreased FA, increased MD, and increased RD values in certain brain regions of recovered COVID-19 patients, such as the left cingulum, left anterior corona radiate, and left internal capsule