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[DOI] [PMC free article] [PubMed] [Google Scholar] 88.Naidu A.S., Wang C.K., Rao P., Mancini F., Clemens R.A., Wirakartakusumah A., Chiu H.F., Yen C.H., Porretta S., Mathai I., et al

Why receptor subtype work matters for interpretation A common question is which receptor subtype is doing the work. A 2025 mechanistic study investigated AMY receptor subtype dependence and reported that cagrilintides body weight lowering effects depended on AMY1R and AMY3R in their models, which provides a more concrete receptor anchored explanation than general appetite language