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The recommended dato-DXd dose is 6 mg/kg, with a maximum of 540 mg for patients with a weight of 90 kg or greater

Its typical to experience some discomfort after an intramuscular injection

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Common experiences after the first injection include: Mild soreness or redness at the injection site (usually resolves within 12 days) Slight improvement in energy levels or mood No immediate noticeable change (particularly common if deficiency is severe) Rarely, mild side effects such as headache or dizziness Some patients report their urine becoming brighter or more intensely coloured following injection, which occurs because excess B12 is excreted renally