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Additionally, CHAC1 is implicated in the induction of apoptosis upon As(III) exposure, as evidenced by increased levels of apoptotic markers and caspase-3 cleavage in cells with intact CHAC1 expression

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doi: 10.1002/mrd.22801 180 NixonBAitkenRJ

Investigational Neurostimulation Techniques Transcutaneous auricular vagus nerve stimulation (tVNS) , in which electrical stimulation is applied through the skin at a location behind the ear, is a non-invasive variation on VNS