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coli model (JI132) of OS (Leu et al., 2017, p

The first step in treatment is a thorough skin examination to determine what type of melasma you have: epidermal (superficial), dermal (deep), or mixed

Consequently, these all lead to more severe DFU

The discrepancy could be due to the difference in cell models and the high rapamycin concentration (100 nM) used in that study which may have induced cell stress 24