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[] Efficacy of paclitaxel is because of little therapeutic index and enhanced transportation

A recent report showed that TAA-mediated hepatocyte pyroptosis in mice can be attenuated by administration of an anaerobic bacterial species named Parabacteroides distasonis by modulating intestinal bile acid metabolism [260]

BsAbs are genetically engineered immunotherapeutics whose cardinal advantage is their capacity to engage two distinct epitopes with a single molecule, thereby overcoming limitations inherent to conventional monoclonal antibodies [19, 20]