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Nitric oxide inhibition of cAMP synthesis in parotid acini: regulation of type 5/6 adenylyl cyclase

The dsRNA replicative intermediate is a potent pathogen-associated molecular pattern (PAMP) sensed by pattern recognition receptors (PRRs) in the cytoplasm (RIG-I-like receptors (RLRs)) and the endosome (Toll-like receptor 3 (TLR3))