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Luteolin inhibits autophagy in allergic asthma by activating PI3K/Akt/mTOR signaling and inhibiting Beclin-1-PI3KC3 complex

( E ) HK2 cells were cotransfected with pRL-TK and pGL3- GCLM -P2 or pGL3- GCLM -M2 with or without REST overexpression, and harvested for luciferase assay ( n = 3)

The compound is often discussed in relation to mitochondria, the structures responsible for generating ATP, the molecule that powers nearly every biological process

3.2 Toll-like receptor signaling pathways TLRs are a family of transmembrane proteins primarily responsible for mediating the bodys innate immune defense, functioning as the initial line of defense against disease-causing microbes