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Description

, commonly called black seed, belongs to the Ranunculaceae family and is grown and distributed in many parts of the world, particularly in Asian, Middle Eastern, Far Eastern, and East Mediterranean regions 15,16

In fact in IBD has been reported an upregulation of the pore-forming claudin-2 and down-regulation of occludin, particularly claudin-5 and -8 in Crohn's disease and claudin-4 and -7 in UC (83, 86, 326)