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GLP-1 receptor activation slows gastric emptying, which reduces the rate of postprandial glucose absorption and attenuates the postprandial glucose excursion an effect that becomes measurable within the first weeks of the escalation phase even at the 2mg starting dose

While he doesn't rate himself on a scale of one to 10 like Marvin, Leander feels happy with how he looks now, "80% of the time"

The PS for adjustment of toxicities was composed using body surface area, age, histology, relapse after surgical resection, ECOG-PS, comorbidities, chemotherapy line, reduced dosage requirement status, and duration of premedication as independent variables, and the C-statistic of the ROC curve analysis was 0.808

2020;124:109849 Zhang T, Zhang Y, Cui MY, Jin L, Wang YM, Lv FX, et al