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As a Nrf2 activator, urolithin A not only protects kidney against oxidative stress via promoting Nrf2 translocating into nucleus (Zhang et al., 2022c), but also ameliorates hyperuricemic nephropathy via enhancing PINK1-associated mitophagy in renal TECs (Zhang et al., 2022a)

66,67 Sarcopenia Sarcopenia, loss of muscle mass, strength, and function that occurs with increasing age, involves some of the same metabolic conditions as NAFLD