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191 Although evidence is mixed, botulinum toxin use in trigger point injections may be helpful for reducing symptoms in people with myofascial pain syndrome, a condition characterized by localized muscle and connective tissue pain

The day 3 SOWS (primary endpoint) was significantly lower in the lofexidine group than in the placebo (6.32 vs 8.67, p = 0.021)

Therefore, targeting the metabolic reprogramming of effector T cells and Treg cells during tumor progression will be a critical strategy for future cancer therapies