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SKU: 20769605913
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Description

(106) confirmed that SIN activates Nrf2 signaling, thereby downregulating M1-type cytokines while upregulating Arg-1, IL-10, and HO-1

Drug Dev Ind Pharm 39:587592

The interaction with Nod1 leads to activation of NFkB and expression of genes encoding for pro-inflammatory cytokines such as IL-8, resulting in chronic inflammation, which is the hallmark of the pathogenesis of Hp-induced GC (Fig