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In particular, L-carnitine reduces the expression of glial fibrillary acidic protein, inducible nitric oxide synthase, ubiquitin and caspase 3 typical markers of cell stress

doi: 10.1073/pnas.1011383107 39 LababidiH.SalernoP

Paclitaxel induces CIPN by altering inositol trisphosphate (IP 3 ) receptor phosphorylation and intracellular calcium flux

The most common side effects are gastrointestinal, including nausea (occurring in 20-30% of patients), diarrhea, vomiting, constipation, and abdominal discomfort