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Mitochondrial DNA damps induce inflammation and insulin resistance

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This heightened risk can stem from impaired taste and smell perception, which diminishes the appeal of food (e.g., hyposmia), as well as difficulties with preparing and consuming meals

Such a setup would precisely delineate the NSC-derived paracrine factors (e.g., BDNF, VEGF [18, 32], TGF-) responsible for suppressing microglial activation and promoting an anti-inflammatory phenotype, independently of in vivo complexities