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It modulates growth-factor signaling (VEGF, FGF) and supports fibroblast activity, which is central to tendon, ligament and gut-lining repair

Therefore, additional, high-quality research would be needed to allow definite conclusions to be reached. Further complicating any assessments of the effects of berberine is the lack of uniformity in the amounts and formulations of berberine used in different studies, as well as the study participants themselves many of whom already had health conditions such as diabetes or fatty liver disease, which might have influenced the results

Govindan et al

Results of intense pure-tone stimulation on auditory thresholds of the goldfish (Carassius auratus) indicated that stimulation at 300 and 500 Hz produce lower threshold shifts than at 800-1,000 Hz (Popper and Clarke 1976)