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For example, a meta-analysis found that two copies of the MTHFR C677T variant (A/A, homozygous) increase the relative risk of heart disease by 38%.[ref][ref] However, not all studies agree, and a large prospective study (n=6,000) found that older people with two copies of the C677T allele were at a 30% decreased risk of death from cardiovascular disease when other parameters were included.[ref] The increased risk is not just due to high homocysteine

[DOI] [PubMed] [Google Scholar] Pinto J.T., Krasnikov B.F., Alcutt S., Jones M.E., Dorai T., Villar M.T., Artigues A., Li J., Cooper A.J.L

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Yes it supports immune function, liver detoxification, cellular repair and oxidative-stress reduction, which is why it features in broader detox and metabolic health programs