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eLife 6 , e29503 (2017)

Several studies have previously explored the otoprotective effects of NAC alone in both animals [10,21,22,23] and humans [24,25,26]

During this two-week incubation period, we noticed the skin tissues treated with high concentrations of MB (5.0 M and above) started to appear blue after 3 days, suggesting that MB dosage needs to be limited to avoid its colorant side effect on skin appearance