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Oct 24: Servier on Tuesday won its fifth FDA approval for Tibsovo (ivosidenib tablets)which also happens to be the first and only targeted therapy for patients with relapsed or refractory (R/R) myelodysplastic syndromes (MDS) with a susceptible IDH1 mutation

The 4.5 mg dose produced 10.8% mean weight loss at 26 weeks

Liao H-J, Chen H-T, Chang C-H

The overlap and complementarity of aerobic exercise and tDCS in pathways such as BDNF, dopamine, and glutamate provide a biological basis for their synergistic enhancement (Steinberg et al., 2019