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Abbreviations ALA: Alpha-linolenic acid ICHD-3: International Classification of Headache Disorders-3 VAS: Visual analog scale MI: Migraine index HDR: Headache diary result MHIS: Migraine headache index score DASS-21: 21-Item Depression, Anxiety, and Stress Scale HIT-6: Headache Impact Test-6 MSQ: Migraine-Specific Quality of Life BMI: Body mass index IPAQ: International Physical Activity Questionnaire MET/h/day: Metabolic equivalent hours per day ANCOVA: Analysis of covariance ITT: Intention-to-treat LOCF: Last observation carried forward NSAIDs: Non-steroidal anti-inflammatory drugs PUFAs: Polyunsaturated fatty acids MUFA: Monounsaturated fatty acid CoQ10: Coenzyme Q10 HIS: International Headache Society References Steiner TJ, Stovner LJ

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Results: A total of 28 RCTs were eligible for the current systematic review, including 1,340 hemodialysis patients (671 intervention, 669 control)