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Osteopontin, secreted by a variety of cells, is the molecule that links inflammation and liver recovery/regeneration and, in addition to being an extracellular matrix protein is also a pro-inflammatory cytokine and is considered to have the greatest prognostic value in predicting liver transplantation in patients with DILI compared to other promising biomarkers such as ccK18/K18 and MCSFR [269]

A randomized, double-blind, placebo-controlled study of histone deacetylase type 6 inhibition for the treatment of painful diabetic peripheral neuropathy