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Mitochondrial Ca2+ is essential for activating key dehydrogenases in the TCA cycle, such as pyruvate dehydrogenase (PDH), IDH and -KGDH, which facilitate NADH and FADH2 production

on the effect of BR on the glucose kinetics, muscle metabolism, AMPK signaling and oxygen consumption, showed that the acute BR consumption had no significant effects on the glucose disposal, Acetyl-CoA carboxylase (ACC) phosphorylation, muscle metabolism, oxygen consumption, or RER during the moderate-intensity physical activity in healthy men ( In addition to muscle strength, improving muscle endurance during the resistance training can be due to the role of NO, because it participates in the regulation of blood pressure (95) by vasodilatory, along with the capability to prevent blood coagulation (96)