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In mitochondria, ROS are generated predominantly at electron transport chain (ETC) complexes and through electron leakage, resulting in the partial reduction of molecular oxygen and the formation of superoxide anion O 2 [175]

*Correspondence: Dan Zhou, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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