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In my line of work, I see plasmapheresis being used for serious neurological, hematologic and autoimmune conditions, and even then it is done with extreme caution

Vitamin B12 Deficiency Among People Taking PPIs: A study in the Journal of the American Medical Association revealed that people who took such acid-suppressing drugs for at least two years were two-thirds more likely to have a vitamin B12 deficiency compared to people not taking powerful acid suppressors

It's important to note that individual responses to BPC-157 may vary, and factors like body weight, metabolism, and the severity of the condition can influence the appropriate dosage

Acta Biochimica Polonica