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Bevacizumab plus fluoropyrimidine-based chemotherapy as initial therapy for metastatic disease is considered standard of care and provides a survival benefit as compared with combination chemotherapy alone

These controlled-release platforms address the limitations of traditional fast-release donors by achieving spatiotemporally precise H 2 S delivery matched to pathological microenvironments, laying groundwork for clinical applications in metabolic disease complications

Commenters suggested that CMS implement the proposed transfer of care modifier changes in the CY 2025 PFS final rule for tracking purposes only and delay payment changes associated with these modifiers until CY 2026

Maintenance Therapy Maintenance therapy is recommended for patients who experience recurrent ulcers