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Branching chain amino acids (leucine, isoleucine, valine) particularly important for protein synthesis signaling

Although FOXO4s specific effects on mitochondria are as direct as the other peptides above, it is known to regulate the expression of genes involved in oxidative stress response and energy metabolism, which can impact mitochondrial function indirectly (Liu, 2019)

( f ) Relative peak intensity of representative metabolites between the control (n = 7 mice) and Cx3cr1-CreER;DTA (n = 11 mice) groups, including betaine, l-citrulline, GSH, choline, and -aminobutyric acid.Data are presented as the mean SEM

Su presencia en el organismo depende del equilibrio interno y de la carga que el cuerpo debe gestionar en detoxificacin celular