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Design, synthesis, characterization, docking studies, cytotoxic and anti-leishmanial activity

Based on these observations, we focused our attention on the effect of Bmal1 deletion on NAD + metabolism

Moreover, in TNF--stimulated ECs, the copper-dependent ATOX1-TRAF4 interaction promotes nuclear translocation and initiates ROS-dependent inflammatory responses, solidifying this axis as a promising therapeutic target [45]