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TIGAR, a TP53-induced regulator of glycolysis and apoptosis, plays a crucial role in energy metabolism, autophagy, stem cell differentiation and cell survival (80)

Abstract The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is an unprecedented global health crisis

Accordingly, the aim of this review was to provide a complementary overview of the recently available scientific literature on the strategy of using nutraceuticals in boosting the immune system under the COVID-19 pandemic

Recently, a structure-based screening has led to the discovery of the first NAPRT activators based on 1,2-dimethylbenzimidazole scaffolds 231 , but evidence for these compounds in boosting NAD + metabolism is still lacking