glutathione persister cells

glutathione persister cells peroxidase 4‐dependent glutathione high‐consumption drives acquired platinum chemoresistance in lung cancer‐derived brain metastasis - Liu - 2021 - Clinical and Translational Medicine Frontiers | Drug-tolerant persister cells:

Name: glutathione persister cells peroxidase 4‐dependent glutathione high‐consumption drives acquired platinum chemoresistance in lung cancer‐derived brain metastasis - Liu - 2021 - Clinical and Translational Medicine Frontiers | Drug-tolerant persister cells:
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Frontiers Drug tolerant persister cells: the deadly survivors in hematological malignancies Selective Small Molecule Activator of Patient Derived GPX4 Variant ACS Chemical Biology Drug tolerant persister cells in head and neck squamous cell carcinoma: Molecular mechanisms and therapeutic opportunities ScienceDirect Persister cancer cells: Iron addiction and vulnerability to ferroptosis: Molecular Cell

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10.1186/s13287-022-02831-1 38 PossematoR.MarksK

Interestingly, when growing in proline medium, in which the gdh3/gdh3 mutant cells failed to undergo morphogenesis, they exhibited an overall reduction in extracellular metabolite levels when compared to the wild-type, with the exception of nicotinate, malate, and succinate levels

Indeed, L2HGDH silencing or addition of cell permeable L2HG reduced global DNA 5hmC modifications (Fig

14 H 22 CuN 6 O 4 GHK-Cu Mechanism of Action Chelates Cu in a square-pyramidal coordination geometry, with labile axial positions available for ternary-complex formation