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Curcumin increases intracellular ROS levels and a treatment with an antioxidant partially reverses the anti-proliferative effects of curcumin Since many curcumin-binding candidates identified in this study (CBR1/3, GSTP1/O1, NQO1/2, AKR1C1/D1, PRDX1, GLO1, and ADH1A shown in Table 1) belong to the enzymes involved in the metabolism of ROS and oxidative-stress products (such as Reactive Carbonyl Species, RCS) 18 , and because curcumin inhibits the enzymatic activity of CBR1 19 , GSTP1 20 , NQO1 21 , and GLO1 22 in vitro , we speculated that the treatment with curcumin up-regulates intracellular ROS levels in CML-derived leukemic cells

Antibodies were generated against key surface proteins of Plasmodium gametocytes, ookinetes, and sporozoites

These alumni, faculty, staff, and friends have made significant contributions to FACS Alumni initiatives, the college, the profession and/or society in general

As a result, aging is considered a key predictive marker for the development of PDD (Aarsland et al., 2017, 2021)