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Authors showed upregulation of transcripts related to inflammation, wounding and defence responses, complement and coagulation and cytokinecytokine receptor interaction pathways (24)

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doi: 10.1038/nature22973

High levels of PUFAs are located in the outer photoreceptor segment and produce substantial amounts of intracellular ROS, making the retina especially susceptible to damage from oxidative stress (166) ( Figure 3 )