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Preprint at bioRxiv (2026)

Notch was considered active if 4 of 5 Notch targets ( HES1, HES2, HEY1, HEY2 and NRARP ) 24 were overexpressed by 1SD of the NCs median

Habits and vulnerability or resilience to stress - impact on depressive disorders

Furthermore, studies on HDAC6 have shown that inhibiting HDAC6 can protect mice from experimental stroke-induced brain injury by regulating oxidative stress through activation of the NRF2/HO-1 pathway [66]